Apr 17 2009 01:02 PM ET

'Grey's' exclusive: 'Big Bang' babe checks in!

Kaleycuoco_lThe list of awesome guest stars appearing in Grey’s Anatomy’s two-hour finale on May 14 just got a little longer. At last night’s Big Bang Theory event at PaleyFest ‘09, leading lady Kaley Cuoco revealed to EW exclusively that she’s Seattle Grace-bound.

“I am working on Grey’s Anatomy next week,” she confirmed. “It is a big ol’ secret. I have no clue what I am doing. I swear on my life that I have no idea what I am playing because it is the finale and they are keeping it under wraps until the last possible moment.”

Adding to the mystery, Cuoco said she didn’t even have to audition for the top-secret part. “They called me directly last week and asked if I would do a part on the finale episode,” she explains. “I didn’t hesitate because I am a fan of the show, and it’s a huge show so it’s probably good for the career, too. And I haven’t been able to do any drama in a long time.

“My guess is that I will be a patient of some kind,” she continues. “I’m practicing my scared-sad-I’m-dying face.”

Okay, guys, help me solve this mystery. Who do you think she’s playing? Personally, I’m not buying the random patient theory. Anyone can play that. This feels bigger. Think, people. We can do this! (Reporting by Carrie Bell)

More TV Scoop:
Will Big Bang go there with Penny and Sheldon?
Law & Order recast!
Double wedding on Chuck

Comments (1-30) of 121 Add your comment

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  • Jon

    Relative of Izzie? Sister?

  • mike

    I would guess Izzy’s daughter, but I think Kaley Cuoco is too old to play the part (no offense to Kaley just that Izzy’s not that old to have a grown daughter) unless they are changing time. Maybe a relative of someone, or a patient.

  • Nabroleon

    I think she will play Angela Merkel from Germany.

  • Adam

    Definitely related to Izzie! By the way, she is sooooo hot!
    http://tvdonewright.com/2009/04/17/tv-tonight-friday-april-17th-2009/

  • kb

    I agree…she’s related to Izzie somehow.

  • Steph

    I’m guessing it has something to do with Izzy. They could pass for family. The patient thing is too obvious for such a secret!

  • B

    izzie’s maid of honor?

  • Woody7

    She’s Izzy’s sister or something. They look similar, so that would be my guess.

  • outside agitator

    she has sex with the ghost of someone who died when a bomb exploded in the er after a ferry ran aground pinning Mer under the smokestack. the guy almost survived when Izzie held his hand while Derek choppered to Bangkok to obtain the kidney of a rare monkey for transplant.
    Kaley says it was gonna be a crossover ep with Lost but Grey’s plot was too ridiculous.

  • Emily

    Maybe Izzie has a dream about her daughter growing up? Shondra likes to have seasons make full circles so since the season started with dreams, maybe it will end with dreams.

  • Tom

    One of Derek’s Sisters, berhaps? Or Arizona’s ex girlfriend.

  • coco

    Izzie’s sister

  • Adam

    Izzie’s…. ex-Girlfriend? (Sorry, had a fantasy moment there)… ummmmmmmmm
    http://tvdonewright.com/2009/04/17/tv-tonight-friday-april-17th-2009/

  • Jen

    As long as she has nothing to do with the Owen/Cristina “curveball”, I really don’t care.

  • byates

    Izzy’s sister who comes in to save Izzy with a bone marrow transplant.

  • tdf

    It is a pilot role to test audience reception of her replacing the role of Dr. …

  • Babsy

    My guess would be Izzie’s sister too :) or somehow related to her …

  • Adam

    SAVE Izzie? I thought she was on her way out.
    http://tvdonewright.com/2009/04/17/tv-tonight-friday-april-17th-2009/

  • Vicky

    “I’m practicing my scared-sad-I’m-dying face.” Haha, awesome.

  • Erin

    “Tom
    Or Arizona’s ex girlfriend.”
    LMAO! In my dreams!!!! That’d be awesome.
    I was actually thinking Arizona’s sister, but Izzie’s sister sounds more reasonable.

  • Adam

    She could be an angel of death. Hey, you never know!
    http://tvdonewright.com/

  • Chris

    How about Izzie’s long ago adopted out baby?

  • Kyle

    Dang…see others thought this–but immediately too I was like—Izzie’s sis! Since Sharon Lawrence is coming on as her Mom, so…

  • Michelle

    As long as she has NOTHING to do with the Owen/Cristina curveball, I don’t really care. Maybe she has something to do with George’s potential fatal wounding?

  • Carly

    Maybe she’s playing a young Izzie in a flashback?

  • Michelle

    As long as she stays far away from Owen, then I’m good. Maybe she has something to do with George’s Army thing? Like she’s in his unit when he gets wounded? That would be far more interesting than being Izzie’s long lost sister or something.

  • Meghan

    Izzy’s daughter…magically grown up thanks to the beauty of the TV aging process

  • Meghan

    Izzy’s daughter…magically grown up thanks to the beauty of the TV aging process

  • CatClaws

    Ya, I can see her as a relative of Izzie’s.
    And by the way…what is it with all of the “spam junk” and LINKS to other sites on here? Very annoying.

  • nykolus

    the new, improved erica hahn???

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